Anti-IgE in severe persistent allergic asthma
نویسندگان
چکیده
منابع مشابه
Anti igE thErApy in AllErgic AsthmA And AllErgic rhinitis
The last few decades have seen a rise in the prevalence of allergic diseases, including asthma and allergic rhinitis. The prevalence asthma is estimated to be around 300 million globally and around 35% in Europe and Australasia and 60 million people in the United States are affected by rhinitis. In India prevalence asthma is estimated to be around 2.38% and 20% to 26% people suffer from allergi...
متن کاملAnti-IgE Therapy with Omalizumab Decreases Endothelin-1 in Exhaled Breath Condensate of Patients with Severe Persistent Allergic Asthma
Background: Omalizumab is a humanized monoclonal antiIgE antibody, especially useful for the treatment of severe persistent allergic asthma, inadequately controlled despite regular therapy. Objectives: The aim of the study was to determine the effect of omalizumab treatment on changes in endothelin-1 (ET-1), which plays an important role in the development of airway inflammation and remodeling ...
متن کاملAnti-IgE therapy with omalizumab decreases endothelin-1 in exhaled breath condensate of patients with severe persistent allergic asthma.
BACKGROUND Omalizumab is a humanized monoclonal anti-IgE antibody, especially useful for the treatment of severe persistent allergic asthma, inadequately controlled despite regular therapy. OBJECTIVES The aim of the study was to determine the effect of omalizumab treatment on changes in endothelin-1 (ET-1), which plays an important role in the development of airway inflammation and remodeling...
متن کاملOmalizumab decreases IgE production in patients with severe allergic asthma
printing supported by . Visit Chiesi at Stand B2.10 MONDAY, SEPTEMBER 3RD 2012 cates that age and sex are the major risk factors. Detailed physiological mechanisms of the changing sex ratio are not fully known. We investigated the influence of gender in anti-IgE treated asthmatics. Methods: We pooled data from ten published studies from 1999 with more of our data of severe persistent asthmatics...
متن کاملAnti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives.
Asthma is a disorder of the airways involving various inflammatory cells and mediators and characterised by bronchial hyperresponsiveness, chronic inflammation and structural alterations in the airways, also known as remodelling. IgE is an important mediator of allergic reactions and has a central role in allergic asthma pathophysiology, as it is implicated in both the early and late phase alle...
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ژورنال
عنوان ژورنال: Respirology
سال: 2007
ISSN: 1323-7799,1440-1843
DOI: 10.1111/j.1440-1843.2007.01016.x